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San Angelo is a city in as well as the county seat of Tom Green County, Texas, United States. The location is within the Concho Valley, a spot of West Texas between the Permian Basin to the northwest, Chihuahuan Desert to the southwest, Osage Plains to the northeast, and also Main Texas to the southeast. Based on a 2014 Census estimation, San Angelo has a complete human population of 100,450. The city is the main city and also center of the San Angelo metropolitan area, that has a human population of 118,182.